Structure House Presents Data Correlating Weight Loss, Reduction of Diabetes ...

DURHAM, N.C. & EMERYVILLE, Calif.--( BUSINESS WIRE )--Structure House, an internationally recognized residential weight loss center, today presented data from a research study of obese individuals in a residential weight loss program showing a correlation among degree of weight loss, reduced cardiometabolic risk factors including cholesterol, triglycerides, and blood pressure, and lowered PreDx® Diabetes Risk Score (DRS). The data also showed that greater weight loss was associated with greater reduction in participants’ diabetes risk score or DRS. PreDx DRS is a multi-marker fasting blood test that assesses markers of inflammation, fat cell function, and glucose metabolism, and categorizes individuals as low, moderate, or high risk for diabetes conversion within 5 years. Developed by Tethys, the PreDx DRS has been shown to be significantly more accurate than HbA1c or fasting glucose in predicting incident diabetes. The data presented today by Structure House represent the first study to demonstrate that obese individuals can lower their PreDx DRS through acute lifestyle changes. This study also suggests that PreDx DRS may be used to provide specific and individualized information to patients about changes in risk resulting from health behavior changes, and such information may provide added motivation to patients to adopt behaviors that can reduce their disease risk.

“We regularly see significant health improvements in participants who complete our four-week diabetes program, and we are excited that this partnership with Tethys validates the effectiveness of simple lifestyle changes in decreasing the PreDx DRS associated with a lower incidence of type 2 diabetes several years later.”

“We believe that these study results show that PreDx DRS could be a valuable component of an effective diabetes prevention program, and that an individual’s PreDx DRS can be lowered quickly following weight loss and reduction of other cardiovascular risk factors. Other studies have shown that the drop in DRS is associated with a significant decrease in long-term risk of diabetes,” said Mickey S. Urdea, PhD, Tethys Chief Scientific Officer. “Further, the results show that the greater the weight loss, the greater the reduction in an individual’s DRS, suggesting that the DRS can be an effective informational tool in motivating overweight individuals to reduce their risk of developing type 2 diabetes.

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Structure House Presents Data Correlating Weight Loss, Reduction of Diabetes ...

risk factors including cholesterol, triglycerides, and blood pressure, and lowered PreDx® Diabetes Risk Score (DRS). The data also showed that greater weight loss was associated with greater reduction in participants' diabetes risk score or DRS.



ADA: Intensive Tx No Better than Good Routine Diabetes Care
ADA: Intensive Tx No Better than Good Routine Diabetes Care

The usual care group achieved an 11.7 mm Hg reduction in systolic blood pressure and 1.2 mmol/L lower LDL with treatment by standard European guidelines, reductions that were nearly as good as the 13.7 mm Hg and 1.3 mmol/L reductions with intensive



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Studies Show Effect of BYDUREON(TM) on A1C and Weight for Up to Three Years

BYDUREON-treated patients also experienced improvements from baseline in several cardiometabolic risk markers, including systolic blood pressure (-2.1 mmHg), total cholesterol (-9.9 mg/dL), LDL cholesterol (-7.0 mg/dL) and triglycerides (-12 percent).




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Worst pills, best pills, a consumer's guide to avoiding drug-induced death or illness

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Major lifestyle modifications shown to lower high blood pressure include weight reduction in those who are overweight or obese.23 In addition, ...

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Advances in psychology research

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Federation Proceedings

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High Blood Pressure for Dummies

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The Blood Pressure Cure, 8 Weeks to Lower Blood Pressure Without Prescription Drugs

The Blood Pressure Cure, 8 Weeks to Lower Blood Pressure Without Prescription Drugs

the American Chemical Society, that participants in the other two groups achieved an equal degree of blood pressure reduction,aver- aging 12 mm Hg systolic ...

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